Postdoc at Eli Lilly

Posted: 02 22, 2017

Description:

TECHNICAL SERVICES & MANUFACTURING SCIENCE: Post-Doctoral Scientist: Full Time (Fixed Duration)

Company Overview: Lilly, a leading innovation-driven corporation is developing a growing portfolio of pharmaceutical products by applying the latest research from its own worldwide laboratories and from collaborations with eminent scientific organizations. Headquartered in Indianapolis, Ind., Lilly provides answers – through medicines and information – for some of the world’s most urgent medical needs. Founded over 137 years ago, the company has sustained a culture that values excellence, integrity and respect for people. This has resulted in Lilly frequently being ranked as one of the best companies in the world at which to work. Lilly knows its business has prospered because of its employees – people with a talent for innovation and a passion for making a difference by finding treatments for the most stubborn diseases; people whose talent is matched by their generosity, and people with strong values and a determination to prevail, regardless of the challenges. Join our team – and make a difference in improving health for people all over the world.

Responsibilities

Post-Doctoral Scientists at Lilly are responsible for:

Ensuring reliability of our manufacturing systems
Searching for and implementing continuous improvements
Driving technical projects
Maintaining our processes in a state of compliance with US and global regulations
Designing and developing drug processes and delivery systems
The position is a Post-Doctoral scientist position in the Technical Services/Manufacturing Sciences (TS/MS) organization. The position will be made available beginning Feb 1, 2017 and will provide technical and scientific support within a dynamic manufacturing environment for development of commercial purification processes for E.coli derived products. The successful candidate will be responsible for designing and executing experiments to advance process knowledge, process optimization and production technical transfer, as needed.

Scientists actively contribute to the TS/MS organization, and have extensive opportunities for involvement in cross-functional teams. This position allows for development of a comprehensive understanding of the pharmaceutical industry, Good Manufacturing Practices (GMP), Regulatory Requirements, and the essential role scientists play in creating solutions for Eli Lilly and Company.

Key Objectives/Deliverables:

Understanding the scientific principles required for manufacturing intermediates and bulk drug substances, including the interaction of chemistry and equipment.
Understand the chemistry and stability of biomolecules.
Develop appropriate laboratory-scale models for key process steps in purification of E.coli – derived products.
Design, conduct, and analyze statistically-designed experiments to deepen process understanding and optimize processing conditions.
Understand scale-up requirements and, as needed, partner with the pilot plant to conduct appropriate scale-up work.
Provide technical support process development areas if needed.
Document all work in an appropriate manner.
Mentor lab associates to enhance their technical capabilities.
Participate in technology transfer as needed.
Travel 0 – 10%

LOCATION: Indianapolis, IN

Qualifications:

Basic Requirements:

Ph.D. in scientific disciplines of Biochemistry, Biology, or Chemistry.
Understanding of protein chemistry and purification (preferred)
Demonstrated record of scientific achievement
Demonstrated problem solving abilities
Ability to work well independently, as well as in teams

To Apply:

With questions, or to apply, contact:

Dr. Nicole M. Lawrence, PhD
Research Scientist- TS/MS
Large Molecule External Manufacturing
Eli Lilly and Company
lawrence_nicole_m@lilly.com 

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